5 Best Multivitamins for Men and Women in 2025: Expert Picks

Multivitamins are among the most widely used supplements globally. You may wonder about the reason. Multivitamin supplements have several health benefits. For instance, they support your immune system, bone, muscle, and heart health, and fill nutritional gaps. 

There are hundreds of brands on the market claiming to be “the best,” making it challenging for you to choose one that suits your dietary needs. However, before choosing a supplement, you should consider several aspects, including ingredient bioavailability, scientific research, transparency, and accessibility.

To help you decide on what’s suitable for you, this guide provides information about the world’s five leading multivitamin brands. Among them, ACTIVIT stands out as a trusted choice for its clean, natural, plant-based, and bioavailable formulation.

Let’s get started with sharing crucial factors to choose supplements! 

Factors We Considered When Choosing These Supplements

• Ingredient quality and bioavailability
• Certifications and safety standards
• Nutrient diversity and dosage
• Clean-label formulation
• Brand reputation and accessibility

• ACTIVIT

Ingredients and Bioavailability: 24 highly bioavailable ingredients (12 vitamins, 10 minerals, and 2 dietary supplements). Serving per Container: 30 tablets (1 tablet daily). Certifications and Quality Standards: ISO, GMP, USP, NSF, JECFA, and DRAP.

What’s notable: With a comprehensive formulation, it provides complete nutrition to support overall health. This plant-based, clean-label formulation contains no allergens, unnecessary binders, artificial additives, colors, sweeteners, or flavors.

It features vitamin D3 with MK-7 (K2) combination to promote bone strength and optimal calcium absorption. It includes methylated B-vitamins and chelated minerals in active, bioavailable forms, such as L-methylfolate (B9), methylcobalamin (B12), magnesium malate, and zinc bisglycinate for superior absorption and effectiveness.

Considerations before buying: ACTIVIT offers one comprehensive multivitamin rather than a broad product range, focusing on a well-researched, high-quality formulation. However, its availability may be limited in certain regions or on online platforms.

• Pure Encapsulations O.N.E. Multivitamin

Ingredients and Bioavailability: 25 nutrients (12 vitamins, 9 minerals, and 4 dietary ingredients). Serving per Container: Convenient counts (30, 60, 120 tablets). Certifications and Quality Standards: GMP Certified, NSF for Sport, and hypoallergenic formula verified. 

What’s notable: Designed for sensitive individuals, Pure Encapsulations is free from common allergens like wheat, soy, tree nuts, dairy, eggs, peanuts, sesame, and gluten. Their clean-label formulation excludes coatings, unnecessary binders, fillers, and preservatives, ensuring a pure hypoallergenic formulation.  

Considerations before buying: While Pure Encapsulations O.N.E. uses quality ingredients like vitamin C as ascorbic acid, choline as choline bitartrate, zinc as zinc citrate, and vitamin A as acetate, they are in standard forms rather than the most advanced bioavailable options. It also comes at a higher cost per serving and has limited availability in retail stores.

• Thorne Basic Nutrients (Two Capsules Daily)

Ingredients and Bioavailability: 25 essential nutrients (12 vitamins, 9 minerals, and 4 dietary ingredients). Serving per Container: 60 capsules (30 servings per bottle; 2 capsules per serving). Certifications and Quality Standards: GMP certified, serves as an official partner of UFC, and NSF certified for Sport.

What’s notable: Thorne uses active and methylated nutrient forms, such as methylcobalamin, L-5-MTHF, and chelated minerals that the body can absorb more effectively. With antioxidants, including tocopherols and lutein from marigold extract, and boron for bone and joint support, the formulation provides optimal health benefits. Capsules are clean-labeled and free from coatings, binders, or preservatives.

Considerations before buying: Although bioavailable, Thorne provides basic forms of nutrients, such as vitamin C as ascorbic acid and vitamin A as palmitate. Besides, two capsules daily may be less convenient than other one-a-day nutrient solutions. With a higher price point, the availability can also be limited in certain retail channels. 

• One A Day Essentials Multivitamin

Ingredients and Bioavailability: 12 essential vitamins and minerals (11 vitamins and 1 mineral). Serving per Container: 150 tablets (1 tablet daily). Certifications and Quality Standards: Meets GMP standards.

What’s notable: One A Day is a trusted brand that delivers a clean formulation free from artificial sweeteners, dairy, and wheat allergens, making it suitable for sensitive individuals. It provides comprehensive B vitamin coverage and optimal support for energy metabolism.

Considerations before buying: Though cost-effective, One A Day still uses standard nutrient forms, such as folic acid instead of methylfolate, ascorbic acid instead of liposomal vitamin C, and cyanocobalamin instead of methylcobalamin. With a smaller nutrient range (around 12 core nutrients), it also provides modest quantities, such as 45 mg calcium (3% DV) and 400 IU of vitamin D (50% DV).

• Nature Made Multivitamin with Iron

Ingredients and Bioavailability: 23 essential vitamins and minerals (13 vitamins and 10 minerals). Serving per Container: 130 tablets (one tablet daily). Certifications and Standards: USP verified and manufactured in compliance with the FDA’s cGMP guidelines.

What’s notable: As a trusted brand, Nature Made provides clean formulations free from gluten, artificial colors, and flavors. This iron-based formula (18mg, 100% DV) is especially best for women who are at a higher risk of low iron levels during their childbearing age.

Considerations before buying: Delivers basic forms of nutrients, such as folic acid instead of methylfolate, cyanocobalamin instead of methylcobalamin, and zinc oxide instead of chelated zinc. Also, it provides lower levels of calcium (160 mg, 12% DV) and magnesium (100 mg, 24% DV), inadequate quantities compared to premium formulas.

Expert Tips for Safe Supplement Use

• Certifications – check for GMP, USP, ISO, or JECFA to ensure product safety. 
• Labels – read carefully for allergens, serving size, and active ingredients. 
• Bioavailability – prefer forms that absorb better, such as methylated vitamins and chelated minerals. 
• Consultation – consult a healthcare provider before starting a supplement regimen if you are on medications.
• RDA – take dosage according to the Recommended Daily Allowance (RDA).  
• Third-party testing – choose trusted brands with transparent labeling and third-party quality testing.

To Sum Up

How to choose the best multivitamin supplement? To find the best supplement, focus on bioavailable ingredient forms, safety standards, and clean formulation free from additives and allergens. Supplement brands like ACTIVIT follow strict quality standards and rigorous testing to ensure the safety and effectiveness of the formulation. Before starting a new supplement regimen, consult your healthcare providers.